Neurotuberculosis: Control of Steroid-Refractory Paradoxical Inflammatory Reaction With Ruxolitinib
نویسندگان
چکیده
منابع مشابه
Ruxolitinib in steroid refractory graft-vs.-host disease: a case report
BACKGROUND Allogeneic hematopoietic stem cell transplantation (HSCT) is potentially curative in a variety of hematological malignancies. Graft-vs.-host disease (GvHD) remains a life-threatening complication. Standard treatment is high-dose (HD) corticosteroids. Steroid-refractory (SR) GvHD is associated with poor prognosis. At present, second-line treatment is ill-defined and includes a number ...
متن کاملSystemic steroid treatment of paradoxical upgrading reaction in patients with lymph node tuberculosis.
Sir—We appreciate the comments by Sartin et al. [1] on our article [2] encouraging routine HIV testing. For HIV testing to become a routine part of medical care, procedural barriers, including signed informed consent and pretest counseling, need to be reexamined. The policy of obtaining signed informed consent prior to HIV testing was created to protect the privacy of patients at a time when th...
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Epilepsy is a neurological disease of the central nervous system. It is estimated that about 50-70 million people worldwide suffer from this chronic disorder and 20 to 30% are resistant to conventional anti-epileptic drugs. In the epilepsy therapeutic arena, there is real need for developing novel antiepileptogenesis treatments that offer a way to prevent the onset or the progression of the dis...
متن کاملTuberculosis paradoxical reaction.
T is endemic in this part of the world. We frequently encounter patients with both pulmonary and extrapulmonary tuberculosis regardless of whether they are infected with human immunodeficiency virus (HIV) or not. It is not uncommon for physicians to see clinical or radiological, or both, worsening of the disease while their patient is on anti-tuberculous treatment, the so-called paradoxical rea...
متن کاملInflammatory paradoxical reaction occurring in tuberculosis patients treated with HAART and rifampicin.
The introduction of highly active antiretroviral treatment (HAART) during tuberculosis treatment may be followed by a systemic inflammatory and paradoxical reaction with flare of symptoms and lymph node enlargement. This reaction has also been observed in association with the treatment of disseminated Mycobacterium avium complex (MAC) infection, Cytomegalovirus and other opportunistic infection...
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ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2019
ISSN: 2328-8957
DOI: 10.1093/ofid/ofz422